Welcome to the Forum!
The R100 GS is a great bike capable of most any task short of top speed trophy's and motocross.
As pointed out, there are a few known issues, the drive shaft being the main one (30k - 60k miles, then you replace or risk it breaking). Parts and upgrades are still widely available. A better shock, and upgraded (progressive) fork springs make a big difference to handling and durability. The BMW bags are ok for tarmac only duty. For city use I'd consider mounting the low fender and put on street tires.
This bike doesn't give up much to the street models unless you are short. The advantage is that when you decide to pack in your day job and head for South America, the keys will already be in your pocket!
Enjoy.
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