I know nothing about the Adventure panniers, but I wholeheartedly endorse the Zega boxes. I have a set on my R1100GS that I have logged lots of miles on and am completely satisfied. I have 41 liter boxes on both sides of the bike, but had to change the exhaust to the low pipe to fit them. Since I haven't used the GS for really rough roads, the low pipe hasn't been an issue.
Good Luck
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