We were there last summer. No problem, about two hours ride from Nukus to Moynaq, former fishermen port. Decent road for Central Asian standards. If you think you're on the wrong road, ask locals. Everyone's friendly and helpful. Go see the boats, Museum of the Aral sea in Moynaq, old fish canning plant. Great experience.
The only real annoyance is the lack of fuel. No petrol at the petrol stations, just LPG. We had no problem getting petrol at the reception of our hotel. In a day or two you get used to carry extra fuel in mineral water bottles ;-)
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