From Uyuni they are building a new road that will save all the trouble with the thick mud suggested by Desert Soul. This can be terrible depending on the time of year. Just 6 weeks ago when everything was drier the old roads were too muddy for me on my Africa Twin. The new road is not on most of the maps but is a consolidated gravel based road. I reckon this might help you get across to the border post at Ollague or certainly speed up the route south to the lakes. I posted a better description a few weeks ago if you care to check that out.
Good luck!
Matt
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