I'll list three because South America is too big for just one.

The road from San Pedro de Atacama, Chile, to Jama, Argentina. 100 miles. I liked it so much, I did it three times. I left San Pedro at 6 AM, arrived in Jama at about 10- stopping for tons of pics. I had a cup of coffee (with a fly in it- made me vomit), then I rode back to San Pedro de Atacama. I gassed up (thanking the gods of gas tanks for my 11 gallons) and rode as fast as I dared (100 mph, baby!) back to Jama. I think the road tops out around 16,500 feet.

The road from Nasca to Cusco. Holy shit this was ****ing epic. I've heard it described as beautiful but it kicked my ass. At one point coming around a curve there was a bus down a cliff a few hundred feet. People were building a shrine. They said 28 people died. I hit a bad stretch of potholes and broke my speedo cable. I rode the whole thing in one sitting- 660 km. I saw my first flamingos. Amazing and the hardest ride I have ever done.

The road from Rio Gallegos to Ushuaia- and back. On the way back, leaving Ushuaia, the snow on the mountains is amazing. The views were kind of like the Rocky Mountains in the fall- only more beautiful and more amazing. Snow covered jagged peaks and red forests and perfect road, except for about 100 miles of ripio in the rain with the mud coming off in a fine bloody mist. And it was windy. I finished the ripio completely covered in red mud. The mud stuck to the exhaust on the bike and it's still there, even though I'm with the bike in Wisconsin. The mud baked on like fancy ceramic.

There were other great roads- if we can count Central America, I really liked the road from San Cristobal de las Casas, Mexico, to La Mesilla. And the coast in El Salvador was nice. Add all of Colombia.

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Latin America Ride Report
Wisconsin to Alaska Ride Report