I would definitely not go to Afghanistan with my GF... in fact I´d probably not go there for any riding trip right now. (Never been there, so could be wrong, but to me, it just really sounds like a bad idea, esp. that two-up part!)
I did once ride with my GF to India, via Iran and Pakistan, and especially Western Pakistan was – and still is, probably now even more than back then – a troubled region, but people seem to ride and drive through there all the time, and very few have had any security related problems. So that route, or via the Stans to China, and then Northern Pakistan (via the Karakoram Highway), those are the two “main” routes between Europe and India. In your case, the Pamirs would be closer to that latter option. But because of winter, you probably can´t do it until late Spring.
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