Malaria and malariaprevention medicine are quite complicated topics.
First of all there are at least 5 different malariabug species. Some places in the world have only one specie of this bug, some places several.
There are also a least 5 different medicines preventing malaria currently on the market. Some of malaria bug species some places in the world has developed recistance to some of types of medicine used to prevent malaria. Thus some docktors now recommend a combination of different pills.
Bear in mind also that even taking malaria pills that actually works youre still not 100 % protected.
Bear also in mind that some of the malaria prevention medicines can give relatively heavy side effects.
You should also read about Dengue fever as I think thats a more common disease to catch in SE Asia.
Anyhow here is a link to some malaria prevention medicines with pros and cons and side effects etc issues by US health authorities.
CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria
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