I remember looking at the Tanezrouft route 20yrs ago trying to work out whether it was possible for an unsupported bike to do it but concluded that it was just about impossible. Not only the 800+ mile range needed (and that if the fuel stations in the south actually had fuel) but the remoteness as well pushed it well beyond what I was happy to risk on my own. Algerian politics imploded shortly afterwards and that was that.
As has been mentioned the only overland route to The Gambia atm is the Atlantic route through Morocco, WS, Mauri and Senegal. You'll not be able to do that from Tunisia without returning to Europe first.
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