I have Distanzias on my XT600E and I love them. Very grippy wet or dry, but the downside is the soft compound doesn't wear well. It's a compromise I am happy to make, although my use is probably 99/1 rather then 80/20. I doubt if they would be much good in mud, although they cope with gravel well. I've had them on for about 4k miles, and both front and rear are shot to bits.
I have Avon Gripsters (not my choice, came with the bike) on my XT660R - same sizes I believe and a broadly similar chassis layout - and they are good on tarmac too. I haven't had them long enough to comment on wear rates. From the pattern, which is more open than the Distanzias, I would imagine they would cope with mud and sand better, but still nowhere near a proper off-road tyre.
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