There appears to be a dearth of responses from folk with actual trailer experience.
My negative opinion is still held especially for monster trailers.
You might preserve some of the fun and mobility of a motorcycle with a small single -wheel- in - line trailer , provided it has a HIGH DRAWBAR which will not strike or hang up on TOPES.
If you are riding a big Harley it should have enough carrying capacity for you r stuff , without a trailer.
Bring a small compact tent and a sleeping bag and your absolute essentials in clothing. Pack it all on the bike and in the side luggage.Bring money . There is no way to avoid needing the latter.
A trailer suggests bringing a lot of frilly stuff , cooking gear , food, cooler .The kitchen sink .

PS. The " Panamericana " as an identifiable single road does not exist . It is a stringing together of a set of nationally numbered highways which was thought up as a tourism development gimmick back in the 20th century . It exists as a marked route only on some maps these days . Very rarely will you see north of Panama any type of road marker denoting"
" Panamericana" .It does have excellent high mountain parts in Guatemala though.
Trying to follow it will actually limit your fun experience of many parts of the countries it crosses.
Try to put together your own wandering route , not limited by some old road trip of others.

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http://advrider.com/index.php?thread....207964/page-5 then scroll down to post #93