Most of the the cannabis region is between Fes and Chefchaouen, East of Fes is more your normal agriculture.
The RN8 north out of Fes takes you through a hot spot of cultivation, and for the love of God (which ever type takes your fancy) avoid the RN419 along Barrage El Wahda, by far the worst road I've encountered out there, curiously every town or village had more mechanics than shops. Otherwise road consitions are pretty good now.
If you've been away since the 2000's the rate of progress and infrastructure development will shock you
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